diff --git a/src/cmd/cgo/internal/testsanitizers/libfuzzer_test.go b/src/cmd/cgo/internal/testsanitizers/libfuzzer_test.go
index 85c8f7bbfb..9f548d66ea 100644
--- a/src/cmd/cgo/internal/testsanitizers/libfuzzer_test.go
+++ b/src/cmd/cgo/internal/testsanitizers/libfuzzer_test.go
@@ -95,6 +95,8 @@ func libFuzzerSupported(goos, goarch string) bool {
 		default:
 			return false
 		}
+	case "loong64":
+		return true
 	default:
 		return false
 	}
diff --git a/src/internal/fuzz/counters_supported.go b/src/internal/fuzz/counters_supported.go
index a71d98d266..7d3b92408d 100644
--- a/src/internal/fuzz/counters_supported.go
+++ b/src/internal/fuzz/counters_supported.go
@@ -2,7 +2,7 @@
 // Use of this source code is governed by a BSD-style
 // license that can be found in the LICENSE file.
 
-//go:build (darwin || linux || windows || freebsd || openbsd) && (amd64 || arm64)
+//go:build ((darwin || linux || windows || freebsd || openbsd) && (amd64 || arm64)) || loong64
 
 package fuzz
 
diff --git a/src/internal/fuzz/counters_unsupported.go b/src/internal/fuzz/counters_unsupported.go
index 156919ec2e..93b99e5b09 100644
--- a/src/internal/fuzz/counters_unsupported.go
+++ b/src/internal/fuzz/counters_unsupported.go
@@ -8,7 +8,7 @@
 //
 // If you update this constraint, also update internal/platform.FuzzInstrumented.
 //
-//go:build !((darwin || linux || windows || freebsd || openbsd) && (amd64 || arm64))
+//go:build !((darwin || linux || windows || freebsd || openbsd) && (amd64 || arm64)) && !loong64
 
 package fuzz
 
diff --git a/src/internal/platform/supported.go b/src/internal/platform/supported.go
index ad8dc93086..262ba14739 100644
--- a/src/internal/platform/supported.go
+++ b/src/internal/platform/supported.go
@@ -72,7 +72,7 @@ func FuzzSupported(goos, goarch string) bool {
 // instrumentation. (FuzzInstrumented implies FuzzSupported.)
 func FuzzInstrumented(goos, goarch string) bool {
 	switch goarch {
-	case "amd64", "arm64":
+	case "amd64", "arm64", "loong64":
 		// TODO(#14565): support more architectures.
 		return FuzzSupported(goos, goarch)
 	default:
diff --git a/src/runtime/libfuzzer_loong64.s b/src/runtime/libfuzzer_loong64.s
new file mode 100644
index 0000000000..1c885bd7a9
--- /dev/null
+++ b/src/runtime/libfuzzer_loong64.s
@@ -0,0 +1,112 @@
+// Copyright 2025 The Go Authors. All rights reserved.
+// Use of this source code is governed by a BSD-style
+// license that can be found in the LICENSE file.
+
+//go:build libfuzzer
+
+#include "go_asm.h"
+#include "textflag.h"
+
+// Based on race_loong64.s; see commentary there.
+
+#define RARG0 R4
+#define RARG1 R5
+#define RARG2 R6
+#define RARG3 R7
+
+#define REPEAT_2(a) a a
+#define REPEAT_8(a) REPEAT_2(REPEAT_2(REPEAT_2(a)))
+#define REPEAT_128(a) REPEAT_2(REPEAT_8(REPEAT_8(a)))
+
+// void runtime·libfuzzerCall4(fn, hookId int, s1, s2 unsafe.Pointer, result uintptr)
+// Calls C function fn from libFuzzer and passes 4 arguments to it.
+TEXT	runtime·libfuzzerCall4<ABIInternal>(SB), NOSPLIT, $0-0
+	MOVV	R4, R12	// fn
+	MOVV	R5, RARG0	// hookId
+	MOVV	R6, RARG1	// s1
+	MOVV	R7, RARG2	// s2
+	MOVV	R8, RARG3	// result
+
+	MOVV	g_m(g), R13
+
+	// Switch to g0 stack.
+	MOVV	R3, R23	// callee-saved, preserved across the CALL
+	MOVV	m_g0(R13), R14
+	BEQ	R14, g, call	// already on g0
+	MOVV	(g_sched+gobuf_sp)(R14), R3
+
+call:
+	JAL	(R12)
+	MOVV	R23, R3
+	RET
+
+// void runtime·libfuzzerCallWithTwoByteBuffers(fn, start, end *byte)
+// Calls C function fn from libFuzzer and passes 2 arguments of type *byte to it.
+TEXT    runtime·libfuzzerCallWithTwoByteBuffers<ABIInternal>(SB), NOSPLIT, $0-0
+	MOVV    R4, R12	// fn
+	MOVV    R5, RARG0	// start
+	MOVV    R6, RARG1	// end
+
+	MOVV    g_m(g), R13
+
+	// Switch to g0 stack.
+	MOVV    R3, R23	// callee-saved, preserved across the CALL
+	MOVV    m_g0(R13), R14
+	BEQ	R14, g, call	// already on g0
+	MOVV    (g_sched+gobuf_sp)(R14), R3
+
+call:
+	JAL	(R12)
+	MOVV    R23, R3
+	RET
+
+// void runtime·libfuzzerCallTraceIntCmp(fn, arg0, arg1, fakePC uintptr)
+// Calls C function fn from libFuzzer and passes 2 arguments to it after
+// manipulating the return address so that libfuzzer's integer compare hooks
+// work.
+// The problem statement and solution are documented in detail in libfuzzer_amd64.s.
+// See commentary there.
+TEXT	runtime·libfuzzerCallTraceIntCmp<ABIInternal>(SB), NOSPLIT, $0-0
+	MOVV	R4, R12	// fn
+	MOVV	R5, RARG0	// arg0
+	MOVV	R6, RARG1	// arg1
+	// Save the original return address in a local variable
+	MOVV	R1, savedRetAddr-8(SP)
+
+	MOVV	g_m(g), R13
+
+	// Switch to g0 stack.
+	MOVV	R3, R23	// callee-saved, preserved across the CALL
+	MOVV	m_g0(R13), R14
+	BEQ	R14, g, call	// already on g0
+	MOVV	(g_sched+gobuf_sp)(R14), R3
+
+call:
+	// Load address of the ret sled into the default register for the return
+	// address.
+	MOVV	$ret_sled(SB), R1
+	// Clear the lowest 2 bits of fakePC. All Loong64 instructions are four
+	// bytes long, so we cannot get better return address granularity than
+	// multiples of 4.
+	AND	$-4, R7
+	// Load the address of the i'th return instruction from the return sled.
+	// The index is given in the fakePC argument.
+	ADDV	R7, R1
+	// Call the function by jumping to it and reusing all registers except
+	// for the modified return address register R1.
+	JMP	(R12)
+
+// The ret sled for Loong64 consists of 128 br instructions jumping to the
+// end of the function. Each instruction is 4 bytes long. The sled thus has
+// the same byte length of 4 * 128 = 512 as the x86_64 sled, but coarser
+// granularity.
+#define RET_SLED \
+	JMP	end_of_function;
+
+TEXT	ret_sled(SB), NOSPLIT, $0-0
+	REPEAT_128(RET_SLED);
+
+end_of_function:
+	MOVV	R23, R3
+	MOVV	savedRetAddr-8(SP), R1
+	RET